SrasV1, Main, Exploration, bibRecord, 004A14

Antibody Avidity Maturation during Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

Identifieur interne : 004A14 ( Main/Exploration ); précédent : 004A13; suivant : 004A15

Antibody Avidity Maturation during Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

Auteurs : Paul K. S. Chan [Hong Kong] ; Pak-Leong Lim [République populaire de Chine] ; Esther Y. M. Liu ; Jo L. K. Cheung ; Danny T. M. Leung [République populaire de Chine] ; Joseph J. Y. Sung

Source :

The Journal of Infectious Diseases [ 0022-1899 ] ; 2005.

RBID : ISTEX:5DD0BEB62B64B1A8E923C9787736EDCE8986FDE0

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Affinité des anticorps (physiologie), Anticorps antiviraux (physiologie), Facteurs temps, Femelle, Humains, Immunoglobuline G (physiologie), Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Syndrome respiratoire aigu sévère (immunologie), Virus du SRAS (immunologie).
MESH :
- immunologie : Syndrome respiratoire aigu sévère, Virus du SRAS.
- physiologie : Affinité des anticorps, Anticorps antiviraux, Immunoglobuline G.
- Adulte, Adulte d'âge moyen, Facteurs temps, Femelle, Humains, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Antibodies, Viral (physiology), Antibody Affinity (physiology), Female, Humans, Immunoglobulin G (physiology), Male, Middle Aged, SARS Virus (immunology), Severe Acute Respiratory Syndrome (immunology), Time Factors.
MESH :
- chemical , physiology : Antibodies, Viral, Immunoglobulin G.
- immunology : SARS Virus, Severe Acute Respiratory Syndrome.
- physiology : Antibody Affinity.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Time Factors.

Abstract

The maturation of virus-specific immunoglobulin G avidity during severe acute respiratory syndrome–associated coronavirus infection was examined. The avidity indices were low (mean ± SD, 30.8% ± 11.6%) among serum samples collected ⩽50 days after fever onset, intermediate (mean ± SD, 52.1% ± 14.1%) among samples collected between days 51 and 90, and high (mean ± SD, 78.1% ± 8.0%) among samples collected after day 90. Avidity indices of 40% and 55% could be considered as cutoff values for determination of recent (⩽50 days) and past (>65 days) infection, respectively. Measurement of antibody avidity can be used to differentiate primary infection from reexposure and to assess humoral responses to candidate vaccines

Url:

https://api.istex.fr/ark:/67375/HXZ-DWX5S810-H/fulltext.pdf

DOI: 10.1086/430615

Affiliations:

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<front><div type="abstract">The maturation of virus-specific immunoglobulin G avidity during severe acute respiratory syndrome–associated coronavirus infection was examined. The avidity indices were low (mean ± SD, 30.8% ± 11.6%) among serum samples collected ⩽50 days after fever onset, intermediate (mean ± SD, 52.1% ± 14.1%) among samples collected between days 51 and 90, and high (mean ± SD, 78.1% ± 8.0%) among samples collected after day 90. Avidity indices of 40% and 55% could be considered as cutoff values for determination of recent (⩽50 days) and past (>65 days) infection, respectively. Measurement of antibody avidity can be used to differentiate primary infection from reexposure and to assess humoral responses to candidate vaccines</div>
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Antibody Avidity Maturation during Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

Antibody Avidity Maturation during Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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